The correlation between iron storage marker (ferritin) and glycated hemoglobin in patient with type two diabetes mellitus

Abstract

Diabetes Mellitus is a major public health concern across the world. because to the related comorbidities. The purpose of this study was to investigate the relationship among serum ferritin and glycated hemoglobin in type 2 diabetic mellitus (T2DM) patients. The research was conducted in Iraq- Baghdad over the course of one year (2020 to 2021). The study included (75 ) T2DM patients and (45) healthy subjects as a control group. Patients with chronic renal disease, chronic liver disease, and COVID-19 infection were excluded. Demographic characters of both groups are recorded. Blood was drawn from groups and tested for ferritin, glycated hemoglobin (HbA1C), fasting blood glucose (FbG), and hemoglobin (Hb). the results showed significant elevation of serum ferritin, HbA1C, FbG in patients with T2DM as a compared with healthy control subjects,  and serum ferritin revealed a positive correlation with HbA1c (Pearson's regression equal to 0.85) in patients with T2DM whereas showed normal correlation in healthy control subject (Pearson's regression = 0.0003). Finally, we can have been concluded from our study the iron storage is represented by ferritin and glycated hemoglobin (HbA1C) are positively correlated in patient with type two diabetes as a compared with healthy control subjects in spite of hemoglobin concentration is not affected by HbA1c and ferritin level in a patient with T2DM.